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Office workers around the world spend many hours each week working at a computer, typing and clicking in much the same way it’s always been done. The computer-keyboard-mouse setup is universal, and, unfortunately, so is the discomfort that can accompany it. The good news is that there are small changes you can implement that can make a big difference.

One of the most effective things to try is a new mouse, especially if you experience discomfort in your hand, wrist, or arm while working. Most office workers aren’t aware of the wide range of alternative mice that are available, so I quizzed the friendly ergonomists here in our office to help break it down for you. These are six of the most popular ergonomic computer mice in our office this year:

1. Evoluent Vertical Mouse

A vertical mouse reduces forearm twisting by allowing the user to mouse with the palm facing sideways instead of down. With a nearly 90-degree angle, this model is a great choice for loyal vertical mouse users. Customize for your perfect fit by choosing between left or right hand, small or large size, and wired or wireless connection.

2. Anker Vertical Mouse

Another true vertical option, this thin and lightweight mouse is ideal for workers on the go or those with a smaller budget. The highly contoured grip surface creates a comfortable resting position for the hand.

3. Logitech MX Vertical Mouse

One of the newer options on the market, this mouse seamlessly blends the neutral posture benefits of a vertical mouse with the support and rounded comfort of a standard mouse. The gentle angle and additional height above the desk surface make this mouse an easy swap for most people switching from a standard mouse.

4. Goldtouch Semi-vertical Mouse

For those who are hesitant to commit to a vertical mouse, this model is a compromise because of the lower slope. The thumb support is well-defined, and an accessory to prevent rubbing on the base of the hand and pinky finger is optional (and recommended).

5. Contour Unimouse

Sometimes flexibility is the key, and this mouse does it the best. With an adjustable angle, dynamic thumb support, and programmable buttons, you’re sure to find a grip that works for you. Even better, change it up throughout the week for better movement.

6. Logitech MX Ergo Trackball Mouse

Trackball-style mice reduce arm movement by engaging the hand and thumb more than a standard mouse. This version comes with a magnetic base so users can choose the most comfortable height and angle. It’s an appropriate choice for people who don’t enjoy the orientation of a vertical mouse or who have limited arm mobility.

Sometimes, switching to a new mouse can take some time to get used to. To ease the transition period, consider holding onto your old mouse for a week or two so you can alternate use when needed. If you still find you’re struggling with your new mouse, you may need to try a different size or style. Let us know if you try any of these options, or if you have a favorite!